When people purchase any of Stigma’s CBD oils — Mint 500mg or 1000mg, Natural 500mg or Modist Dream Oil 500mg — we typically advise that these products are best absorbed when placed beneath the tongue, or sublingually. If you’ve ever wondered why we give this advice, Wikipedia sums it up perfectly: Sublingual administration has certain advantages over oral administration. Being more direct, it is often faster, and it ensures that the substance will risk degradation only by salivary enzymes before entering the bloodstream, whereas orally administered drugs must survive passage through the hostile environment of the gastrointestinal tract, which risks degrading them, by either stomach acid or bile, or by enzymes… Furthermore, after absorption from the gastrointestinal tract, such drugs must pass to the liver, where they may be extensively altered; this is known as the first pass effect of drug metabolism. https://en.wikipedia.org/wiki/Sublingual_administration On January 29, 2020 / Blog / Leave a comment Previous Post Stigma's Shop Awarded Best In State. Next Post CBD and the FDA: Thoughts On What 2020 May Bring.